Birth Control Pill Tied to Slight Rise in Breast Cancer Risk

Newer versions of the birth control pill carry a similar increased risk of breast cancer as earlier ones that were abandoned in the 1990s, a new study reveals.

Woman taking modern formulations of the pill have a 20% increased risk of breast cancer compared with those who’ve never been on hormonal contraception, the study of almost 2 million Danish women found.

“The risk increases with increasing duration of use and persists for more than five years, if used for longer than five years,” said study author Lina Morch, a senior epidemiologist with the University of Copenhagen in Denmark.

Still, experts cautioned that the absolute risk of breast cancer for any one women on the Pill remains very low.

Nevertheless, a similar amount of risk prompted the U.S. Food and Drug Administration to yank high-estrogen formulations of the pill off the market back in the early 1990s, said Mia Gaudet, strategic director of breast and gynecologic cancer research for the American Cancer Society.

“There had been some changes to oral contraceptive formulations in the ‘90s, and there was the hope those formulations would result in a lower risk of breast cancer,” said Gaudet, who was not part of the study. “We see from this data that is not the case.”

The first wave of birth control pills contained doses as high as 150 mg of estrogen. As research began to link estrogen to breast cancer, the FDA took off the market any formulations that had more than 50 mg of estrogen, Gaudet said.